SF 415 255-9510  |  MARIN 415 464-8801

SF 415 255-9510  |  MARIN 415 464-8801

(plated)™ SkinScience

The first and only topical skincare product harnessing the power of platelet-derived exosomes.

(plated) SkinScience If you’re on the cutting-edge of science and skin care products, you know the buzzword of the last few years is “exosomes”. The buzz is earned! Exosomes are impactful ingredients that we’ve wanted to share with our customers. But until now, exosomes have not been shelf-stable and so could not be distributed in home care products.

Now you can harness the power of exosomes and promote cell growth, form new blood vessels, and reduce inflammation by adding Rion Aesthetics’ (plated) SkinScience Intensive Repair Serum and Revitalizing Essence to your daily at-home regimen.

Right now, within your body, platelets are releasing exosomes which have a job to do:

  1. carry beneficial antioxidant enzymes and proteins,
  2. seek out tissue which is damaged or inflamed, and
  3. deliver growth factors to these injured cells.

(plated) SkinScience’s key proprietary ingredient, Renewosomes™, contains trillions of these hard-working exosomes, extracted from human platelets purchased from FDA-compliant platelet banks. Rion Aesthetics’ studies show that while every cell in your body produces exosomes, only platelet-generated exosomes signal soft tissue renewal. From these “renewing” effect exosomes, the key Renewosomes™ are extracted.

From the cellular level, new collagen is stimulated, decreasing redness and wrinkles and:

  • building firmer skin
  • improving luminosity, skin tone, and texture
  • shrinking pore size
  • targeting free radicals and environmental influences which can trigger cellular aging
  • calming the skin
  • reducing dark spots and broken capillaries

Before and after six weeks of use

Before and after six weeks of use

Before and after six weeks of use

Before and after six weeks of use


Two formulations are available. The essence (1 oz) is intended as part of a daily skin care regimen. The serum (0.5 oz) contains double the concentration of Renewosomes™ and is recommended for patients with more damaged skin. Complimentary consultations are available in-person or by phone so you can determine which product is best for you.


Revitalizing Essence
A daily infusion of Renewosomes™ provides a barrier to maintain luminosity and overall skin glow. It provides a calming and radiance-boosting effect against the signs of aging.

Transition to the essence once severe symptoms have been managed by the higher concentration serum.

Apply two pumps as part of your evening regimen.

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Intensive Repair SerumIntensive Repair Serum
A powerful, concentrated blend of Renewosomes™, designed to correct damaged skin. Enriched with growth factors and antioxidants that help your skin rejuvenate the appearance of wrinkles, brown spots, redness, and dullness.

Apply two pumps as part of your evening regimen.


415 255-9510

415 464-8801



Gene V.
I love Hayes Valley Medical and Esthetics! I've been coming for a while now for Botox and filler treatments. Linda is AMAZING! She knows just the right amount of product needed in all the right places to bring out my best facial features. I feel more handsome every time!!

The front desk staff are super sweet and helpful. They always ask exactly what I want and I never feel like I'm being 'upsold' or encouraged to do anything other than what I came in for. I would highly recommend HVME to anybody that is on the unsure about trying some of the services they offer. You won't be disappointed. Thank you!!
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Sadie M.
Jessica is a healing goddess of beauty! I see her for facials and eyelash extensions. Jessica always makes me feel and look better!
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Miss C. A.
I saw Cherie for some Botox and here we are, two days later, and it looks perfect! I know Botox sometimes takes anywhere between a few days to a week or so to totally take effect, so I can't imagine it looking any better than where it's already at. I'm very happy w/ my result. I will definitely be back!
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Cher B.
Sheila and Linda took great care of me and I look younger and vibrant.  I do not trust anyone else for injectables.  Linda is careful, thoughtful, and respectful of one’s budget. I have followed her from Marin into SF and I will continue to follow her where ever she practices.
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Emily N.
I highly recommend Hayes Valley Medical & Esthetics!! All the front desk staff are warm, friendly and professional and Denise is the best for laser, she goes above to make you feel comfortable and at ease. Andrea is exceptional at explaining the services they offer. They are the best in SF in my opinion and I do my research!
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Results May Vary

Receive 10% off your first treatment at either location!