DefenAge™ Skincare FAQ

What makes DefenAge Cosmeceuticals unique?
DefenAge Cosmeceuticals is the only skincare with Age-Repair Defensins, a novel, non-prescription, patent-pending peptide complex known to communicate directly with skin’s master stem cells.

What are Defensins? What do they do?
Defensins are powerful regenerative peptides whose benefits were first linked to the immune system. They are also known for their antimicrobial effects. Recently, the age-repairing nature of these natural peptides was discovered by scientists at Progenitor Biologics™, the parent company of DefenAge Cosmeceuticals, while researching stem cell therapies for wound healing and Type I Diabetes. During the course of their research, our scientists made an extraordinary discovery: two members of the defensin family have surprising benefits for aging skin in cosmeceutical skincare. Alpha-defensin 5 communicates specifically with skin’s Master Stem Cells to unlock the skin’s age-corrective potential. Beta-defensin 3 significantly improves skin’s barrier functions. This discovery was so novel and unexpected we are patenting the use of these peptides for anti-aging purposes.

What are Age-Repair Defensins™? What do they do?
Age-Repair Defensins is our proprietary blend of these powerful regenerative peptides combined with unique supporting molecules in a protective nanocapsule delivery system. The result is age-correcting activity that produces up to 18 years visible reduction in skin aging over 6 weeks of regular use*. DefenAge Cosmeceuticals is the first and only skincare to utilize these revolutionary peptides for their effects in visible age-correction.
* Based on results obtained from a six-week clinical study of participants aged 48-68 using 2-Minute Reveal Masque one-to-two times a week and 24/7 Barrier Repair Cream and 8-in-1 BioSerum twice daily. Results were measured using QuantifiCare™ Clinical Imaging System. Individual results may vary.

Why aren’t skin types and skin analysis important when using DefenAge Cosmeceuticals?
Aging skin is a global condition that occurs in any skin type (dry, oily, normal, combination). Since all aging skin has the same basic needs, we’ve formulated each product for use by all skin types, thereby eliminating the need to analyze your skin. If your skin is aging, you can use our products.

Why do I apply 24/7 Barrier Repair Cream first followed by 8-in-1 BioSerum?
We know this is the reverse of other skin care lines so it probably seems unnatural to you. However, there is a very good reason why we ask you to do this. The cream contains ingredients that help the age-correcting ingredients in the serum to penetrate deeper into your skin’s surface. Putting the serum on first will limit this penetration so you will be less likely to see the dramatic improvements seen and felt by the participants in our clinical studies.

Why don’t you have an eye cream?
It is under development in our laboratory. In the meantime, please be sure to apply the 8-in-1 BioSerum above and below your eyes as directed.

Can I keep using Retin-A®?
Yes, if you want to.

Highlighted Ingredients
• Niacinamide – Soothes, revives the skin’s natural moisture barrier, renews the feel of skin firmness and elasticity and brightens overall skin tone.
• Hyaluronic Acid-Liposome Encapsulated – Promotes hydration and improves texture for remarkably smooth and even skin.
• Sea Whip – Keeps skin calm. Strongest, fastest and most effective soothing ingredient from the sea.

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HAYES VALLEY

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Kirsten S.
Linda and staff are amazing. I am always very happy with my treatment results. It is apparent that she researches various technologies and techniques. The applications are always evolving with new and improved products. Highly recommended.
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Suzanne P.
Excellent service and an overall pleasant experience. Victoria was professional and knowledgeable. She proposed treatments addressing both my anesthetic and medical concerns.. I could not be happier with the results. Also, the Receptionist, Mattie, was pleasant and efficient. I look forward to future treatments.
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Lisa M.
Hayes Valley is the best! Kate did an incredible job with Dysport removing the wrinkles from my forehead, Sandra gave me great abs and glutes with Emsculpt, and Linda gave me my youthful facial structure back with Sculptra. These women are truly amazing. So glad that I found them!
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Gene V.
I love Hayes Valley Medical and Esthetics! I've been coming for a while now for Botox and filler treatments. Linda is AMAZING! She knows just the right amount of product needed in all the right places to bring out my best facial features. I feel more handsome every time!!

The front desk staff are super sweet and helpful. They always ask exactly what I want and I never feel like I'm being 'upsold' or encouraged to do anything other than what I came in for. I would highly recommend HVME to anybody that is on the unsure about trying some of the services they offer. You won't be disappointed. Thank you!!
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Julie S.
This was my first experience with any filler/injection treatment and it was very pleasant, professional and everyone there made me feel safe, welcome and I felt very knowledgeable coming out of my treatment about what to expect. I will absolutely be back!
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Tina B.
Diana at the front desk is so sweet, the medical assistant was amazing & personable and Kate who did my procedure is my favorite! As I walked out and met my husband, I told him how much I enjoy being there & what a good vibe Hayes has.
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Cher B.
Sheila and Linda took great care of me and I look younger and vibrant.  I do not trust anyone else for injectables.  Linda is careful, thoughtful, and respectful of one’s budget. I have followed her from Marin into SF and I will continue to follow her where ever she practices.
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Emily N.
I highly recommend Hayes Valley Medical & Esthetics!! All the front desk staff are warm, friendly and professional and Denise is the best for laser, she goes above to make you feel comfortable and at ease. Andrea is exceptional at explaining the services they offer. They are the best in SF in my opinion and I do my research!
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Kathleen F.
Excellent customer service, advice, and care. Botox and Microneedling. Melonie is a gem. She is extremely knowledgable, sincere and honest. Everyone here is helpful, They carry a fabulous array of skin products too. I am so pleased with my results!
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