RADIESSE for the Décolleté: The First FDA-Approved Biostimulator for Face and Body

RADIESSE is now the first and only regenerative biostimulator with FDA approval for both the face and body, including a new indication for correcting wrinkles in the décolleté. Linda Behla, RN, Founder and Director of Nursing at Hayes Valley Medical Esthetics (HVME), brings over 20 years of injectable expertise to every treatment plan, with all procedures performed under the medical supervision of board-certified plastic surgeon Dr. Yngvar A. Hvistendahl.

In this blog, we'll discuss what makes RADIESSE different from traditional fillers, how this new FDA approval expands your treatment options, and why the décolleté deserves the same attention as the face when it comes to rejuvenation.

What Makes RADIESSE a Regenerative Biostimulator?

RADIESSE is composed of calcium hydroxylapatite (CaHA) microspheres suspended in a carboxymethylcellulose gel carrier. CaHA is a mineral that occurs naturally in human bone and teeth, which makes it highly biocompatible. Unlike hyaluronic acid fillers that add volume by attracting water, RADIESSE activates your body's own regenerative processes to rebuild skin from within.

Here's how the process works:

• Immediate correction: The gel carrier provides instant volume and structural support at the injection site.
• Fibroblast activation: CaHA microspheres stimulate fibroblasts, the cells that produce collagen and elastin.
• Gradual regeneration: As the gel carrier is absorbed, your body breaks down the microspheres while simultaneously depositing new collagen and elastin, resulting in a thicker dermis and improved skin quality over time.

This dual-action mechanism, immediate improvement paired with progressive tissue remodeling, is what sets biostimulators apart from traditional fillers and why Linda Behla, RN, and the HVME team consider RADIESSE a cornerstone of regenerative aesthetics.

Why the Décolleté Matters

The chest is one of the earliest areas to show visible signs of aging, yet it is frequently overlooked in skincare and aesthetic treatment plans. The skin of the décolleté is structurally thinner than facial skin and particularly vulnerable to sun damage, collagen loss, and crepiness.

Several factors make this area especially prone to premature aging:

• Chronic sun exposure: The décolleté receives consistent UV radiation, accelerating the breakdown of collagen and elastin.
• Thin dermal layer: Fewer oil glands and less subcutaneous fat mean the chest loses firmness faster than the face.
• Limited skincare attention: Most daily routines stop below the chin, leaving the décolleté underprotected and undertreated.

Before this approval, RADIESSE had already been used for the décolleté based on published clinical evidence and physician judgment. The FDA’s decision in April 2026 now provides patients with an on-label, clinically validated option specifically designed for this area.

What Does RADIESSE Treat?

With four FDA-approved indications, RADIESSE is one of the most versatile biostimulatory injectables available today. It can address a range of concerns across multiple treatment areas.

Current FDA-approved uses include:

• Facial wrinkles and folds, including nasolabial folds
• Facial lipoatrophy and volume loss
• Hand rejuvenation for volume restoration in the hands
• Décolleté wrinkles using a diluted 1:2 formulation with sterile saline

HVME’s team of Master Injectors tailors every RADIESSE treatment to the individual, adjusting dilution ratios and injection techniques based on the treatment area and each patient’s unique anatomy.

What Results Can You Expect?

RADIESSE delivers both immediate and long-term improvements. Clinical data supporting the décolleté approval showed that more than 80% of patients reported satisfaction with skin tightness, and 90% of providers observed visible improvement in their patients.

Key outcomes include:

• Immediate firmness: The gel carrier provides structural correction from the first treatment.
• Progressive skin quality improvement: New collagen and elastin production continue to develop over weeks to months following treatment.
• Long-lasting results: Effects can last up to two years in the face, with décolleté results studied through 84 weeks.

Recovery is minimal. Most patients experience only mild swelling or bruising and return to their daily routines right away.

Discover What RADIESSE Can Do for You at HVME

RADIESSE’s new FDA approval for the décolleté gives patients a clinically proven, non-surgical way to address one of the most visible and most neglected signs of aging. With over 250 scientific publications, two decades of clinical use, and more than 20 million syringes delivered worldwide, RADIESSE is backed by a depth of evidence that few aesthetic treatments can match.

HVME’s Master Injectors have extensive training with Merz, Allergan, and Galderma, and every treatment is customized under physician supervision to deliver natural-looking results. If you're ready to rejuvenate your face, hands, or décolletage with one of the most researched biostimulators in regenerative aesthetics, schedule your complimentary consultation at Hayes Valley Medical Esthetics today.