Italian Innovation Meets San Francisco's Most Trusted Esthetics Team 

HVME's Esthetics Department, led by Holly Byerly, LE, Director of Esthetics, brings years of hands-on experience with the most advanced skin treatments available. Every PRX by WiQo treatment is performed by a trained clinical aesthetician under the medical supervision of board-certified plastic surgeon Dr. Yngvar A. Hvistendahl. Backed by over 20 years of clinical research and trusted in more than 67 countries, PRX by WiQo represents a new category in non-invasive skin care, and HVME is proud to bring this Italian-engineered technology to patients across San Francisco and Marin County.

What Is PRX by WiQo?

PRX by WiQo is a professional, in-office topical biostimulator system. Unlike traditional chemical peels, which remove the outer layers of skin and require days of visible peeling, PRX treatments bypass the epidermis and work directly within the deeper dermal layers to stimulate collagen production, cell renewal, and skin regeneration. The core PRX formulation combines trichloroacetic acid (TCA) with hydrogen peroxide. The hydrogen peroxide partially neutralizes TCA's effect on the surface of the skin, allowing it to penetrate into the dermis where it activates fibroblasts and promotes neocollagenesis without causing visible exfoliation. The result is firmer, brighter, more hydrated skin with zero downtime. Each treatment takes approximately 15 minutes. The solution is gently massaged into the skin using a precise, clinician-performed technique until fully absorbed. Patients typically notice an immediate glow, with continued improvement over the following weeks as new collagen forms.

Three PRX Treatments, One Customized Approach 

HVME offers three distinct PRX by WiQo formulations, each designed to target different skin concerns. Your clinical aesthetician will recommend the right treatment based on your individual skin type and goals.

PRX Derm Perfexion

The original PRX treatment, formulated with 33% TCA, hydrogen peroxide, and kojic acid. Derm Perfexion is designed for overall skin rejuvenation, helping improve the appearance of firmness, elasticity, and hydration. It is ideal for patients looking to address fine lines, enlarged pores, acne scars, stretch marks, and early signs of aging on the face and body.

PRX Plus

The newest addition to the PRX line, PRX Plus is formulated with Ammonium Trichloroacetate (ATCA) and Homocysteic Acid, an ingredient exclusive to this treatment. PRX Plus is designed for mature or textured skin showing more advanced signs of aging. It targets deep wrinkles, hyperpigmentation, melasma, and uneven skin tone while promoting dermal density and brightness.

PRX-C

PRX-C is formulated specifically for skin that appears dull, gray, or environmentally stressed. This treatment helps enhance the appearance of radiance, luminosity, and resilience while reducing the visible signs of fatigued, devitalized skin. It is an excellent option for patients looking to restore a healthy, vibrant glow.

Background media

Benefits of PRX by WiQo

  • No needles, no peeling, no downtime: Resume your normal routine immediately after treatment.
  • Immediate visible results: Skin appears firmer, smoother, and more radiant after just one session.
  • Long-term collagen stimulation: TCA activates fibroblast production and neocollagenesis for continued improvement over weeks.
  • Safe for all skin types and tones: PRX by WiQo is not photosensitizing and can be used year-round, including summer months.
  • Face and body versatility: Treat the face, neck, décolleté, hands, arms, abdomen, and more.
  • Pairs well with other treatments: PRX can be combined with microneedling, RF treatments, and medical-grade skincare for enhanced results.

Are You a Candidate for PRX by WiQo?

PRX by WiQo may be right for you if you are experiencing:

  • Fine lines, wrinkles, or loss of skin elasticity
  • Dull, tired, or devitalized skin
  • Enlarged pores or uneven skin texture
  • Hyperpigmentation, melasma, or sun damage
  • Acne scars or stretch marks
  • Crepey skin on the neck, chest, or hands
  • Early or advanced signs of facial aging

PRX treatments are safe for men and women of all ages and skin types. You should not receive PRX if you are pregnant or breastfeeding, have active infections or open wounds in the treatment area, or have a known allergy to any of the formulation's ingredients.

Why Choose HVME for PRX by WiQo in San Francisco?

HVME's clinical aestheticians are specifically trained in the PRX application protocol, ensuring precise product layering, proper technique, and optimal results for every patient. With over 30 advanced devices and a comprehensive menu of esthetic and medical treatments, our team can integrate PRX into a broader skin care plan tailored to your unique goals. Three convenient locations in San Francisco and Larkspur make it easy to fit treatments into your schedule.

What to Expect Before, During, and After Treatment

Before Your Treatment:

  • Schedule a consultation with HVME's esthetics team to evaluate your skin and determine which PRX formulation is right for you.
  • Discontinue retinol and aggressive exfoliating products 7 to 15 days before your appointment.
  • If you have recently received BOTOX or dermal fillers, wait at least two weeks before scheduling PRX.
  • Pricing varies based on the treatment area and formulation selected. Your provider will review costs during your consultation.

During Your Treatment:

  • Your provider will cleanse and prepare the skin using WiQo P Solution.
  • The PRX solution is applied and massaged into the skin using a specific technique until fully absorbed.
  • Two to five applications are performed in a single session, depending on your treatment plan.
  • Sessions last approximately 15 minutes for the face and up to 30 minutes for larger treatment areas.
  • Most patients report a mild tingling or warming sensation during application.

After Your Treatment:

  • There is no visible peeling, no photosensitivity, and no required downtime.
  • Skin will appear immediately brighter, firmer, and more hydrated.
  • Mild redness may occur and typically resolves within a few hours.
  • WiQo post-care products are recommended to maintain and extend your results.
  • A full series of four to six sessions, spaced one to two weeks apart, is recommended for optimal results.
  • Maintenance treatments can be scheduled monthly or as recommended by your provider.
Background media

Complementary Treatments

PRX by WiQo pairs well with several treatments available at HVME. Your provider may recommend combining PRX with SkinPen microneedling, Scarlet Pro RF microneedling, DiamondGlow, or clinical facials to amplify your results and create a comprehensive rejuvenation plan.

Experience the PRX Glow at HVME

Discover what PRX by WiQo can do for your skin. Contact Hayes Valley Medical Esthetics at one of our San Francisco or Larkspur locations to schedule your consultation and find out which PRX treatment is the perfect match for your skin goals.

Banner media
Contact us media
Accessibility: If you are vision-impaired or have some other impairment covered by the Americans with Disabilities Act or a similar law, and you wish to discuss potential accommodations related to using this website, please contact our Accessibility Manager.
Contact Us